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A major goal of biologists is to determine the underlying genetic causes of human diseases in order to better understand them and support their prevention and treatment. High-throughput technologies such as linkage analysis, association studies and expression array experiments allow to obtain chromosomal regions associated with genetic conditions but they are costly and time expensive. The ProphNet prioritization system can help in this work by obtaining new relationships or interactions between different biological entities quickly and without costs.
ProphNet has been validated through a variety of test featuring better performance than other state of the art methods.
ProphNet can work with different types of biological entities and relations with different meanings at the same time.
ProphNet allows new data sources to be easily added and combined without modifying underlying algorithms.